ATE17115T1 - Verfahren zur herstellung von kernsubstituierten derivaten der cinnamoylanthranilsaeure und deren zwischenprodukte. - Google Patents
Verfahren zur herstellung von kernsubstituierten derivaten der cinnamoylanthranilsaeure und deren zwischenprodukte.Info
- Publication number
- ATE17115T1 ATE17115T1 AT82304389T AT82304389T ATE17115T1 AT E17115 T1 ATE17115 T1 AT E17115T1 AT 82304389 T AT82304389 T AT 82304389T AT 82304389 T AT82304389 T AT 82304389T AT E17115 T1 ATE17115 T1 AT E17115T1
- Authority
- AT
- Austria
- Prior art keywords
- manufacture
- acid derivatives
- intermediate products
- core substituted
- substituted cinnamoylanthranilic
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- GMEKUFJCKPYDAH-UHFFFAOYSA-N 2-(3-phenylprop-2-enoylamino)benzoic acid Chemical class OC(=O)C1=CC=CC=C1NC(=O)C=CC1=CC=CC=C1 GMEKUFJCKPYDAH-UHFFFAOYSA-N 0.000 title 1
- 239000013067 intermediate product Substances 0.000 title 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- WJUFSDZVCOTFON-UHFFFAOYSA-N veratraldehyde Chemical compound COC1=CC=C(C=O)C=C1OC WJUFSDZVCOTFON-UHFFFAOYSA-N 0.000 abstract 2
- NZHGWWWHIYHZNX-UHFFFAOYSA-N 2-((3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)amino)benzoic acid Chemical compound C1=C(OC)C(OC)=CC=C1C=CC(=O)NC1=CC=CC=C1C(O)=O NZHGWWWHIYHZNX-UHFFFAOYSA-N 0.000 abstract 1
- LZEMYXZYMHWMMN-UHFFFAOYSA-N 2-(phenylcarbamoyl)propanedioic acid Chemical compound OC(=O)C(C(O)=O)C(=O)NC1=CC=CC=C1 LZEMYXZYMHWMMN-UHFFFAOYSA-N 0.000 abstract 1
- 239000012445 acidic reagent Substances 0.000 abstract 1
- -1 cinnamoylanthranilic acid compound Chemical class 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Dental Preparations (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56137344A JPS5838244A (ja) | 1981-09-01 | 1981-09-01 | 核置換シンナモイルアントラニル酸塩およびその製造方法 |
| EP82304389A EP0074725B1 (en) | 1981-09-01 | 1982-08-19 | A method for the production of nuclear substituted cinnamoylanthranilic acid derivatives and intermediates thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE17115T1 true ATE17115T1 (de) | 1986-01-15 |
Family
ID=15196441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT82304389T ATE17115T1 (de) | 1981-09-01 | 1982-08-19 | Verfahren zur herstellung von kernsubstituierten derivaten der cinnamoylanthranilsaeure und deren zwischenprodukte. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US4486597A (en]) |
| EP (1) | EP0074725B1 (en]) |
| JP (1) | JPS5838244A (en]) |
| AT (1) | ATE17115T1 (en]) |
| AU (1) | AU562861B2 (en]) |
| CA (1) | CA1189090A (en]) |
| DE (1) | DE3268129D1 (en]) |
| DK (1) | DK158467C (en]) |
| ES (1) | ES515401A0 (en]) |
| FI (1) | FI75148C (en]) |
| HU (1) | HU186968B (en]) |
| NO (1) | NO159849C (en]) |
| PT (1) | PT75452B (en]) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536346A (en) * | 1983-05-06 | 1985-08-20 | American Cyanamid Company | Aralkanamidophenyl compounds |
| JPS60214766A (ja) * | 1984-04-04 | 1985-10-28 | Terumo Corp | アミド誘導体およびこれを有効成分として含有する５−リポキシゲナ−ゼ作用阻害剤 |
| JPH0784424B2 (ja) * | 1987-04-15 | 1995-09-13 | 味の素株式会社 | チロシン誘導体及びその用途 |
| KR970006473B1 (ko) * | 1987-06-08 | 1997-04-28 | 오노 화아마슈티칼 캄파니 리미팃드 | 신나모일아미드 유도체, 그들의 제조방법, 그들을 함유하는 제약학적 조성물 및 그들의 사용 |
| WO2002055454A2 (en) * | 2001-01-10 | 2002-07-18 | Smithkline Beecham Corporation | Process and product |
| DE10208778B4 (de) * | 2002-02-28 | 2004-08-12 | Thyssenkrupp Stahl Ag | Aus Stahl-Hohlprofilen gebildete Tragstruktur für Fahrzeuge |
| DE10254872A1 (de) * | 2002-11-25 | 2004-06-03 | Symrise Gmbh & Co. Kg | Anthranilsäureamide und deren Derivate als kosmetische und pharmazeutische Wirkstoffe |
| SG10201506526QA (en) * | 2007-12-21 | 2015-09-29 | Fibrotech Therapeutics Pty Ltd | Halogenated analogues of anti-fibrotic agents |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3755603A (en) * | 1970-07-01 | 1973-08-28 | Syntex Corp | Biphenylyloxyacetic acids in pharmaceutical compositions |
| JPS5640710B2 (en]) * | 1973-01-18 | 1981-09-22 | ||
| JPS5848545B2 (ja) * | 1974-04-18 | 1983-10-28 | キツセイヤクヒンコウギヨウ カブシキガイシヤ | シンキホウコウゾクカルボンサンアミドユウドウタイ ノ セイゾウホウホウ |
| JPS511440A (ja) * | 1974-04-18 | 1976-01-08 | Kissei Pharmaceutical | Shinkihokozokukarubonsanjudotai no seizohoho |
| US4337270A (en) * | 1980-05-21 | 1982-06-29 | Hisamitsu Pharmaceutical Co., Inc. | Novel anthranilic acid derivatives |
| JPS568858A (en) * | 1980-06-23 | 1981-01-29 | Hitachi Ltd | Resin sealing type semiconductor device |
-
1981
- 1981-09-01 JP JP56137344A patent/JPS5838244A/ja active Granted
-
1982
- 1982-08-13 AU AU87148/82A patent/AU562861B2/en not_active Expired
- 1982-08-19 AT AT82304389T patent/ATE17115T1/de not_active IP Right Cessation
- 1982-08-19 EP EP82304389A patent/EP0074725B1/en not_active Expired
- 1982-08-19 DE DE8282304389T patent/DE3268129D1/de not_active Expired
- 1982-08-23 PT PT75452A patent/PT75452B/pt not_active IP Right Cessation
- 1982-08-25 FI FI822953A patent/FI75148C/fi not_active IP Right Cessation
- 1982-08-26 CA CA000410210A patent/CA1189090A/en not_active Expired
- 1982-08-31 ES ES515401A patent/ES515401A0/es active Granted
- 1982-08-31 DK DK389582A patent/DK158467C/da not_active IP Right Cessation
- 1982-08-31 NO NO822943A patent/NO159849C/no not_active IP Right Cessation
- 1982-08-31 HU HU822794A patent/HU186968B/hu unknown
-
1984
- 1984-02-07 US US06/577,758 patent/US4486597A/en not_active Expired - Lifetime
- 1984-08-14 US US06/640,588 patent/US4623724A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US4486597A (en) | 1984-12-04 |
| AU8714882A (en) | 1983-03-10 |
| DK389582A (da) | 1983-03-02 |
| JPS5838244A (ja) | 1983-03-05 |
| HU186968B (en) | 1985-10-28 |
| FI75148B (fi) | 1988-01-29 |
| FI75148C (fi) | 1988-05-09 |
| JPH0136462B2 (en]) | 1989-07-31 |
| DK158467C (da) | 1990-10-22 |
| PT75452A (en) | 1982-09-01 |
| NO159849C (no) | 1989-02-15 |
| EP0074725B1 (en) | 1985-12-27 |
| AU562861B2 (en) | 1987-06-18 |
| NO159849B (no) | 1988-11-07 |
| FI822953A0 (fi) | 1982-08-25 |
| ES8307208A1 (es) | 1983-07-01 |
| DK158467B (da) | 1990-05-21 |
| CA1189090A (en) | 1985-06-18 |
| PT75452B (en) | 1984-11-19 |
| EP0074725A1 (en) | 1983-03-23 |
| NO822943L (no) | 1983-03-02 |
| DE3268129D1 (en) | 1986-02-06 |
| ES515401A0 (es) | 1983-07-01 |
| US4623724A (en) | 1986-11-18 |
| FI822953L (fi) | 1983-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |